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Ncf1 (p47phox) Is Essential for Direct Regulatory T Cell Mediated Suppression of CD4+ Effector T Cells

BACKGROUND: Multiple mechanisms have been advanced to account for CD4+FOXP3+ regulatory T cell (Treg)-mediated suppression of CD4+ effector T cells (Teffs) but none appear to completely explain suppression. Previous data indicates that Tregs may affect the microenvironment redox state. Given the inh...

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Detalhes bibliográficos
Main Authors: Efimova, Olga, Szankasi, Philippe, Kelley, Todd W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017100/
https://ncbi.nlm.nih.gov/pubmed/21253614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016013
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