Cardiac Myosin Heavy Chain Isoform Exchange Alters the Phenotype of cTnT-Related Cardiomyopathies in Mouse Hearts

Familial Hypertrophic Cardiomyopathy, FHC, is a clinically heterogeneous, autosomal-dominant disease of the cardiac sarcomere leading to extensive remodeling at both the whole heart and molecular levels. The remodeling patterns are mutation-specific, a finding that extends to the level of single ami...

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Autors principals: Rice, Ron, Guinto, Pia, Dowell-Martino, Candice, He, Huamei, Hoyer, Kirsten, Krenz, Maike, Robbins, Jeffrey, Ingwall, Joanne S., Tardiff, Jil C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016872/
https://ncbi.nlm.nih.gov/pubmed/20004663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.11.018
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