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Calcium-Activated Pathways and Oxidative Burst Mediate Zymosan-Induced Signaling and IL-10 Production in Human Macrophages

Outside of the TLR paradigm, there is little understanding of how pathogen recognition at the cell surface is linked to functional responses in cells of the innate immune system. Recent work in this area demonstrates that the yeast particle zymosan, by binding to the β-glucan receptor Dectin-1, acti...

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Detalhes bibliográficos
Main Authors: Kelly, Erin K., Wang, Lu, Ivashkiv, Lionel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016855/
https://ncbi.nlm.nih.gov/pubmed/20400701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901293
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