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Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger

Endoplasmic reticulum associated degradation (ERAD) is a conserved mechanism to remove misfolded proteins from the ER by targeting them to the proteasome for degradation. To assess the role of ERAD in filamentous fungi, we have examined the consequences of disrupting putative ERAD components in the...

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Dettagli Bibliografici
Autori principali: Carvalho, Neuza D. S. P., Arentshorst, Mark, Kooistra, Rolf, Stam, Hein, Sagt, Cees M., van den Hondel, Cees A. M. J. J., Ram, Arthur F. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016150/
https://ncbi.nlm.nih.gov/pubmed/20922374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-010-2916-5
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