Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger

Endoplasmic reticulum associated degradation (ERAD) is a conserved mechanism to remove misfolded proteins from the ER by targeting them to the proteasome for degradation. To assess the role of ERAD in filamentous fungi, we have examined the consequences of disrupting putative ERAD components in the...

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Detalhes bibliográficos
Main Authors: Carvalho, Neuza D. S. P., Arentshorst, Mark, Kooistra, Rolf, Stam, Hein, Sagt, Cees M., van den Hondel, Cees A. M. J. J., Ram, Arthur F. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Applied Genetics and Molecular Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016150/
https://ncbi.nlm.nih.gov/pubmed/20922374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-010-2916-5
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