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Tau, prions and Aβ: the triad of neurodegeneration

This article highlights the features that connect prion diseases with other cerebral amyloidoses and how these relate to neurodegeneration, with focus on tau phosphorylation. It also discusses similarities between prion disease and Alzheimer’s disease: mechanisms of amyloid formation, neurotoxicity,...

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Detalhes bibliográficos
Main Authors: Reiniger, Lilla, Lukic, Ana, Linehan, Jacqueline, Rudge, Peter, Collinge, John, Mead, Simon, Brandner, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015202/
https://ncbi.nlm.nih.gov/pubmed/20473510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0691-0
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