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Tau, prions and Aβ: the triad of neurodegeneration

This article highlights the features that connect prion diseases with other cerebral amyloidoses and how these relate to neurodegeneration, with focus on tau phosphorylation. It also discusses similarities between prion disease and Alzheimer’s disease: mechanisms of amyloid formation, neurotoxicity,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reiniger, Lilla, Lukic, Ana, Linehan, Jacqueline, Rudge, Peter, Collinge, John, Mead, Simon, Brandner, Sebastian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015202/
https://ncbi.nlm.nih.gov/pubmed/20473510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0691-0
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