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Interplay of T-cell receptor and interleukin-2 signalling in Vγ2Vδ2 T-cell cytotoxicity
Human peripheral blood Vγ2Vδ2 T cells are important for host defence and tumour immunity. Their unusual T-cell receptor (TCR) recognizes small molecule phosphoantigens; stimulated cells produce inflammatory cytokines and are potently cytotoxic for a variety of tumours. However, molecular mechanisms...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3015079/ https://ncbi.nlm.nih.gov/pubmed/20738419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03343.x |
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