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Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation?

Sialic-acid-binding immunoglobulin-like lectins, siglecs, are important immune receptors expressed widely in mammals. A unique feature of siglecs is their ability to bind sialylated glycans and transmit signals to immune cells. The CD33-related siglecs (CD33rSiglecs) form a major subfamily of the si...

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Bibliographic Details
Main Authors: Cao, Huan, Crocker, Paul R
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015071/
https://ncbi.nlm.nih.gov/pubmed/21070233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03368.x
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