Endothelial activation and apoptosis mediated by neutrophil-dependent interleukin 6 trans-signalling: a novel target for systemic sclerosis?

OBJECTIVES: Systemic sclerosis (SSc) is a connective tissue disease associated with significant morbidity and mortality and generally inadequate treatment. Endothelial cell activation and apoptosis are thought to be pivotal in the pathogenesis of this disease, but the mechanisms that mediate this re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Barnes, Theresa C, Spiller, David G, Anderson, Marina E, Edwards, Steven W, Moots, Robert J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Group 2010
Pynciau:
Basic and Translational Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015068/
https://ncbi.nlm.nih.gov/pubmed/21068092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2010.133587
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