Endothelial activation and apoptosis mediated by neutrophil-dependent interleukin 6 trans-signalling: a novel target for systemic sclerosis?

OBJECTIVES: Systemic sclerosis (SSc) is a connective tissue disease associated with significant morbidity and mortality and generally inadequate treatment. Endothelial cell activation and apoptosis are thought to be pivotal in the pathogenesis of this disease, but the mechanisms that mediate this re...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Barnes, Theresa C, Spiller, David G, Anderson, Marina E, Edwards, Steven W, Moots, Robert J
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BMJ Group 2010
Θέματα:
Basic and Translational Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015068/
https://ncbi.nlm.nih.gov/pubmed/21068092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2010.133587
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