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Inhibition of interleukin-6 trans-signaling prevents inflammation and endothelial barrier disruption in retinal endothelial cells.

Vascular inflammation plays a critical role in the pathogenesis of diabetic retinopathy. Recently, Interleukin-6 (IL-6) trans-signaling via soluble IL-6 receptor (sIL-6R) has emerged as a prominent regulator of inflammation in endothelial cells. This study was designed to test the hypothesis that se...

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Vydáno v:Exp Eye Res
Hlavní autoři: Valle, Maria, Dworshak, Janine, Sharma, Ashok, Ibrahim, Ahmed, Al-Shabrawey, Mohamed, Sharma, Shruti
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361696/
https://ncbi.nlm.nih.gov/pubmed/30240585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2018.09.009
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