The Dose Proportionality of Telcagepant after Administration of Single Oral and Intravenous Doses in Healthy Adult Subjects

INTRODUCTION: Telcagepant (MK-0974) is a novel, orally active and selective CGRP receptor antagonist being investigated for acute treatment of migraine. Early clinical data suggested greater than dose proportional increases in exposure following oral administration. The aim of the present studies wa...

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Bibliografische gegevens
Hoofdauteurs: Han, Tae H, Blanchard, Rebecca L, Palcza, John, Martucci, Ashley, Miller-Stein, Cynthia M, Gutierrez, Maria, Panebianco, Deborah, Rippley, Ronda K, Lines, Christopher, Murphy, M Gail
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Inc 2010
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015066/
https://ncbi.nlm.nih.gov/pubmed/21221171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2010.00031.x
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