The Dose Proportionality of Telcagepant after Administration of Single Oral and Intravenous Doses in Healthy Adult Subjects

INTRODUCTION: Telcagepant (MK-0974) is a novel, orally active and selective CGRP receptor antagonist being investigated for acute treatment of migraine. Early clinical data suggested greater than dose proportional increases in exposure following oral administration. The aim of the present studies wa...

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Main Authors: Han, Tae H, Blanchard, Rebecca L, Palcza, John, Martucci, Ashley, Miller-Stein, Cynthia M, Gutierrez, Maria, Panebianco, Deborah, Rippley, Ronda K, Lines, Christopher, Murphy, M Gail
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015066/
https://ncbi.nlm.nih.gov/pubmed/21221171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2010.00031.x
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