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The Dose Proportionality of Telcagepant after Administration of Single Oral and Intravenous Doses in Healthy Adult Subjects

INTRODUCTION: Telcagepant (MK-0974) is a novel, orally active and selective CGRP receptor antagonist being investigated for acute treatment of migraine. Early clinical data suggested greater than dose proportional increases in exposure following oral administration. The aim of the present studies wa...

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Bibliografiske detaljer
Main Authors: Han, Tae H, Blanchard, Rebecca L, Palcza, John, Martucci, Ashley, Miller-Stein, Cynthia M, Gutierrez, Maria, Panebianco, Deborah, Rippley, Ronda K, Lines, Christopher, Murphy, M Gail
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Inc 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015066/
https://ncbi.nlm.nih.gov/pubmed/21221171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2010.00031.x
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