Dynamic subcellular localization of isoforms of the folate pathway enzyme serine hydroxymethyltransferase (SHMT) through the erythrocytic cycle of Plasmodium falciparum

BACKGROUND: The folate pathway enzyme serine hydroxymethyltransferase (SHMT) converts serine to glycine and 5,10-methylenetetrahydrofolate and is essential for the acquisition of one-carbon units for subsequent transfer reactions. 5,10-methylenetetrahydrofolate is used by thymidylate synthase to con...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Read, Martin, Müller, Ingrid B, Mitchell, Sarah L, Sims, Paul FG, Hyde, John E
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014972/
https://ncbi.nlm.nih.gov/pubmed/21129192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-351
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