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Effect of Histamine and Its Methyl Derivatives on Cyclic AMP Metabolism in Gastric Mucosa and Its Blockade by an H(2) Receptor Antagonist
In a cell-free system prepared from guinea pig gastric mucosa, histamine and Nα-methyl-histamine produced dose-dependent stimulation of cyclic AMP formation and 1,4-methylhistamine had a minimal stimulatory effect. N-methyl-N′-(2-[5-methylimidazole-4-yl-methylthio]-ethyl) -thiourea (metiamide), a ne...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1974
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC301469/ https://ncbi.nlm.nih.gov/pubmed/4148625 |
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