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CHARACTERIZATION OF A NOVEL INTERACTION BETWEEN TRANSCRIPTION FACTOR TFII-I AND THE TYROSINE KINASE ITK IN T CELLS
TCR signaling leads to the activation of kinases such as Itk, a key regulatory protein in T lymphocyte activation and function. The homolog of Itk in B cells is Btk, previously shown to bind and phosphorylate the transcription factor TFII-I. TFII-I plays major roles in transcription and signaling. O...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014647/ https://ncbi.nlm.nih.gov/pubmed/19701889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200839031 |
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