CD4+ and CD8+ T cell- and IL-17-mediated Protection against Entamoeba histolytica Induced by a Recombinant Vaccine

Amebiasis in the murine model can be prevented by vaccination with the Gal/GalNAc lectin through a T cell-dependent mechanism. In this work we further decipher the mechanism of this protection. Mice vaccinated with the recombinant “LecA” fragment of the Gal/GalNAc lectin with alum were capable of tr...

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Main Authors: Guo, Xiaoti, Barroso, Lisa, Lyerly, David M., Petri, William A., Houpt, Eric R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014458/
https://ncbi.nlm.nih.gov/pubmed/21095257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.11.013
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