Adjuvant composition and delivery route shape immune response quality and protective efficacy of a recombinant vaccine for Entamoeba histolytica

Amebiasis caused by Entamoeba histolytica is the third leading cause of parasitic mortality globally, with some 100,000 deaths annually, primarily among young children. Protective immunity to amebiasis is associated with fecal IgA and IFN-γ in humans; however, no vaccine exists. We have previously i...

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Vydáno v:NPJ Vaccines
Hlavní autoři: Abhyankar, Mayuresh M., Orr, Mark T., Lin, Susan, Suraju, Mohammed O., Simpson, Adrian, Blust, Molly, Pham, Tiep, Guderian, Jeffrey A., Tomai, Mark A., Elvecrog, James, Pedersen, Karl, Petri, William A., Fox, Christopher B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988657/
https://ncbi.nlm.nih.gov/pubmed/29900011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-018-0060-x
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