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Brain Molecular Aging, Promotion of Neurological Disease and Modulation by Sirtuin5 Longevity Gene Polymorphism

Mechanisms determining characteristic age of onset for neurological diseases are largely unknown. Normal brain aging associates with robust and progressive transcriptome changes (“molecular aging”), but the intersection with disease pathways is mostly uncharacterized. Here, using cross-cohort microa...

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Autors principals: Glorioso, Christin, Oh, Sunghee, Douillard, Gaelle Guilloux, Sibille, Etienne
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014380/
https://ncbi.nlm.nih.gov/pubmed/20887790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.09.016
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