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Brain Molecular Aging, Promotion of Neurological Disease and Modulation by Sirtuin5 Longevity Gene Polymorphism

Mechanisms determining characteristic age of onset for neurological diseases are largely unknown. Normal brain aging associates with robust and progressive transcriptome changes (“molecular aging”), but the intersection with disease pathways is mostly uncharacterized. Here, using cross-cohort microa...

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Bibliografiske detaljer
Main Authors: Glorioso, Christin, Oh, Sunghee, Douillard, Gaelle Guilloux, Sibille, Etienne
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014380/
https://ncbi.nlm.nih.gov/pubmed/20887790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.09.016
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