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Perivascular Delivery of Blebbistatin Reduces Neointimal Hyperplasia after Carotid Injury in the Mouse

Proliferation and migration of smooth muscle cells (SMC) require myosin II activity; thus, we examined whether blebbistatin, a cell-permeable selective inhibitor of myosin II ATP activity, would impair neointimal hyperplasia after vascular injury. Delivery of blebbistatin via a perivascular polymer...

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書誌詳細
主要な著者: Huang, Jianhua, Zhang, Jianxin, Pathak, Alokkumar, Li, Juxiang, Stouffer, George A.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014304/
https://ncbi.nlm.nih.gov/pubmed/20956482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.174615
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