Blood Myeloid Dendritic Cells from HIV-1-Infected Individuals Display a Proapoptotic Profile Characterized by Decreased Bcl-2 Levels and by Caspase-3(+) Frequencies That Are Associated with Levels of Plasma Viremia and T Cell Activation in an Exploratory Study

Reduced frequencies of myeloid and plasmacytoid dendritic cell (DC) subsets (mDCs and pDCs, respectively) have been observed in the peripheral blood of HIV-1-infected individuals throughout the course of disease. Accumulation of DCs in lymph nodes (LNs) may partly account for the decreased numbers o...

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Detalhes bibliográficos
Main Authors: Dillon, Stephanie M., Friedlander, Laura J., Rogers, Lisa M., Meditz, Amie L., Folkvord, Joy M., Connick, Elizabeth, McCarter, Martin D., Wilson, Cara C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014213/
https://ncbi.nlm.nih.gov/pubmed/20962079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01118-10
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