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Domain Structure of Lassa Virus L Protein

The 200-kDa L protein of arenaviruses plays a central role in viral genome replication and transcription. This study aimed at providing evidence for the domain structure of L protein by combining bioinformatics with a stepwise mutagenesis approach using the Lassa virus minireplicon system. Potential...

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Autors principals: Brunotte, Linda, Lelke, Michaela, Hass, Meike, Kleinsteuber, Katja, Becker-Ziaja, Beate, Günther, Stephan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014181/
https://ncbi.nlm.nih.gov/pubmed/20980514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00721-10
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