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A weak DD-carboxypeptidase activity explains the inability of PBP 6 to substitute for PBP 5 in maintaining normal cell shape in E. coli

PBP 5 plays a critical role in maintaining normal cellular morphology in mutants of E. coli lacking multiple PBPs. The most closely related homologue, PBP 6, is 65% identical to PBP 5 but is unable to substitute for PBP 5 in returning these mutants to their wild type shape. The relevant differences...

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Autores principales: Chowdhury, Chiranjit, Nayak, Tapas R., Young, Kevin D., Ghosh, Anindya S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013634/
https://ncbi.nlm.nih.gov/pubmed/20015336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1574-6968.2009.01863.x
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