Phosphorylation of immunity-related GTPases by a Toxoplasma gondii secreted kinase promotes macrophage survival and virulence

Macrophages are specialized to detect and destroy intracellular microbes and yet a number of pathogens have evolved to exploit this hostile niche. Here we demonstrate that the obligate intracellular parasite Toxoplasma gondii disarms macrophage innate clearance mechanisms by secreting a serine threo...

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Bibliografski detalji
Glavni autori: Fentress, Sarah J., Behnke, Michael S., Dunay, Ildiko R., Mashayekhi, Mona, Rommereim, Leah M., Fox, Barbara A., Bzik, David J., Taylor, Gregory A., Turk, Benjamin E., Lichti, Cheryl F., Townsend, R. Reid, Qiu, Wei, Hui, Raymond, Beatty, Wandy L., Sibley, L. David
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013631/
https://ncbi.nlm.nih.gov/pubmed/21147463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.11.005
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