A Maladaptive Role for EP4 Receptors in Podocytes

Inhibition of p38 mitogen-activated protein kinase and cyclooxygenase-2 reduces albuminuria in models of chronic kidney disease marked by podocyte injury. Previously, we identified a feedback loop in podocytes whereby an in vitro surrogate for glomerular capillary pressure (i.e., mechanical stretch)...

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Detalhes bibliográficos
Main Authors: Stitt-Cavanagh, Erin M., Faour, Wissam H., Takami, Kaede, Carter, Anthony, Vanderhyden, Barbara, Guan, Youfei, Schneider, Andre, Breyer, Matthew D., Kennedy, Christopher R.J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013547/
https://ncbi.nlm.nih.gov/pubmed/20671216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121234
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