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Distinct Roles for Basal and Induced COX-2 in Podocyte Injury

Transgenic mice that overexpress cyclooxygenase-2 (COX-2) selectively in podocytes are more susceptible to glomerular injury by adriamycin and puromycin (PAN). To investigate the potential roles of COX-2 metabolites, we studied mice with selective deletion of prostanoid receptors and generated condi...

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Detalhes bibliográficos
Main Authors: Cheng, Huifang, Fan, Xiaofeng, Guan, Youfei, Moeckel, Gilbert W., Zent, Roy, Harris, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736764/
https://ncbi.nlm.nih.gov/pubmed/19643929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009010039
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