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Quantitative Proteomics and Transcriptomics Addressing the Estrogen Receptor Subtype-mediated Effects in T47D Breast Cancer Cells Exposed to the Phytoestrogen Genistein

The present study addresses, by transcriptomics and quantitative stable isotope labeling by amino acids in cell culture (SILAC)-based proteomics, the estrogen receptor α (ERα) and β (ERβ)-mediated effects on gene and protein expression in T47D breast cancer cells exposed to the phytoestrogen geniste...

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Bibliographic Details
Main Authors: Sotoca, Ana M., Sollewijn Gelpke, Maarten D., Boeren, Sjef, Ström, Anders, Gustafsson, Jan-Åke, Murk, Albertinka J., Rietjens, Ivonne M. C. M., Vervoort, Jacques
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013448/
https://ncbi.nlm.nih.gov/pubmed/20884965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.002170
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