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Stable, Non-Destructive Immobilization of Native Nuclear Membranes to Micro-Structured PDMS for Single-Molecule Force Spectroscopy

In eukaryotic cells the nucleus is separated from the cytoplasm by a double-membraned nuclear envelope (NE). Exchange of molecules between the two compartments is mediated by nuclear pore complexes (NPCs) that are embedded in the NE membranes. The translocation of molecules such as proteins and RNAs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rangl, Martina, Nevo, Reinat, Liashkovich, Ivan, Shahin, Victor, Reich, Ziv, Ebner, Andreas, Hinterdorfer, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013320/
https://ncbi.nlm.nih.gov/pubmed/19507204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.200900219
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