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Aberrantly Silenced Promoters Retain a Persistent Memory of the Silenced State After Long-Term Reactivation

A hallmark of aberrant DNA methylation-associated silencing is reversibility. However, long-term stability of reactivated promoters has not been explored. To examine this issue, spontaneous reactivant clones were isolated from mouse embryonal carcinoma cells bearing aberrantly silenced Aprt alleles...

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Bibliografische gegevens
Hoofdauteurs: Oyer, Jon A., Yates, Phillip A., Godsey, Sarah, Turker, Mitchell S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013294/
https://ncbi.nlm.nih.gov/pubmed/21035468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2010.10.006
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