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Aberrantly Silenced Promoters Retain a Persistent Memory of the Silenced State After Long-Term Reactivation
A hallmark of aberrant DNA methylation-associated silencing is reversibility. However, long-term stability of reactivated promoters has not been explored. To examine this issue, spontaneous reactivant clones were isolated from mouse embryonal carcinoma cells bearing aberrantly silenced Aprt alleles...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013294/ https://ncbi.nlm.nih.gov/pubmed/21035468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2010.10.006 |
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