RNAi Screen of DAF-16/FOXO Target Genes in C. elegans Links Pathogenesis and Dauer Formation

The DAF-16/FOXO transcription factor is the major downstream output of the insulin/IGF1R signaling pathway controlling C. elegans dauer larva development and aging. To identify novel downstream genes affecting dauer formation, we used RNAi to screen candidate genes previously identified to be regula...

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Bibliographic Details
Main Authors: Jensen, Victor L., Simonsen, Karina T., Lee, Yu-Hui, Park, Donha, Riddle, Donald L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013133/
https://ncbi.nlm.nih.gov/pubmed/21209831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015902
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