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Therapeutic potential of Trichostatin A to control inflammatory and fibrogenic disorders of the ocular surface

PURPOSE: To examine the effects of a histone deacetylase inhibitor, Trichostatin A (TSA), on the behavior of macrophages and subconjunctival fibroblasts in vitro and on ocular surface inflammation and scarring in vivo using an alkali burn wound healing model. METHODS: Effects of TSA on expression of...

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Main Authors: Kitano, Ai, Okada, Yuka, Yamanka, Osamu, Shirai, Kumi, Mohan, Rajiv R., Saika, Shizuya
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013068/
https://ncbi.nlm.nih.gov/pubmed/21203344
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