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Mass Spectrometry Provides Accurate and Sensitive Quantitation of A2E

Orange autofluorescence from lipofuscin in the lysosomes of the retinal pigment epithelium (RPE) is a hallmark of aging in the eye. One of the major components of lipofuscin is A2E, the levels of which increase with age and in pathologic conditions, such as Stargardt disease or age-related macular d...

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Detalhes bibliográficos
Main Authors: Gutierrez, Danielle B., Blakeley, Lorie, Goletz, Patrice W., Schey, Kevin L., Hanneken, Anne, Koutalos, Yiannis, Crouch, Rosalie K., Ablonczy, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013054/
https://ncbi.nlm.nih.gov/pubmed/20931136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0pp00230e
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