Identification and Functional Characterization of TMEM16A, a Ca(2+)-activated Cl(−) Channel Activated by Extracellular Nucleotides, in Biliary Epithelium

Cl(−) channels in the apical membrane of biliary epithelial cells (BECs) provide the driving force for ductular bile formation. Although a cystic fibrosis transmembrane conductance regulator has been identified in BECs and contributes to secretion via secretin binding basolateral receptors and incre...

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Detalhes bibliográficos
Main Authors: Dutta, Amal K., Khimji, Al-karim, Kresge, Charles, Bugde, Abhijit, Dougherty, Michael, Esser, Victoria, Ueno, Yoshiyuki, Glaser, Shannon S., Alpini, Gianfranco, Rockey, Don C., Feranchak, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013035/
https://ncbi.nlm.nih.gov/pubmed/21041307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164970
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