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Mechanisms of Autoinhibition of IRF-7 and a Probable Model for Inactivation of IRF-7 by Kaposi's Sarcoma-associated Herpesvirus Protein ORF45
IRF-7 is the master regulator of type I interferon-dependent immune responses controlling both innate and adaptive immunity. Given the significance of IRF-7 in the induction of immune responses, many viruses have developed strategies to inhibit its activity to evade or antagonize host antiviral resp...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013033/ https://ncbi.nlm.nih.gov/pubmed/20980251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.150920 |
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