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Surprising Substrate Versatility in SLC5A6: Na(+)-COUPLED I(−) TRANSPORT BY THE HUMAN Na(+)/MULTIVITAMIN TRANSPORTER (hSMVT)
Iodide (I(−)) is an essential constituent of the thyroid hormones triiodothyronine and thyroxine, which are required for the development of the central nervous system in the fetus and newborn. I(−) uptake in the thyroid is mediated by the Na(+)/I(−) symporter (NIS). NIS has gained particular medical...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3012967/ https://ncbi.nlm.nih.gov/pubmed/20980265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167197 |
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