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Surprising Substrate Versatility in SLC5A6: Na(+)-COUPLED I(−) TRANSPORT BY THE HUMAN Na(+)/MULTIVITAMIN TRANSPORTER (hSMVT)

Iodide (I(−)) is an essential constituent of the thyroid hormones triiodothyronine and thyroxine, which are required for the development of the central nervous system in the fetus and newborn. I(−) uptake in the thyroid is mediated by the Na(+)/I(−) symporter (NIS). NIS has gained particular medical...

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Autors principals: de Carvalho, Fernanda Delmondes, Quick, Matthias
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012967/
https://ncbi.nlm.nih.gov/pubmed/20980265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167197
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