Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer

Epithelial ovarian cancer is the leading cause of death among gynecologic malignancies. Diagnosis usually occurs after metastatic spread, largely reflecting vague symptoms of early disease combined with lack of an effective screening strategy. Epigenetic mechanisms of gene regulation, including DNA...

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Библиографические подробности
Главные авторы: Matsumura, Noriomi, Huang, Zhiqing, Mori, Seiichi, Baba, Tsukasa, Fujii, Shingo, Konishi, Ikuo, Iversen, Edwin S., Berchuck, Andrew, Murphy, Susan K.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2011
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012928/
https://ncbi.nlm.nih.gov/pubmed/21156726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.108803.110
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