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Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer

Epithelial ovarian cancer is the leading cause of death among gynecologic malignancies. Diagnosis usually occurs after metastatic spread, largely reflecting vague symptoms of early disease combined with lack of an effective screening strategy. Epigenetic mechanisms of gene regulation, including DNA...

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Detalhes bibliográficos
Main Authors: Matsumura, Noriomi, Huang, Zhiqing, Mori, Seiichi, Baba, Tsukasa, Fujii, Shingo, Konishi, Ikuo, Iversen, Edwin S., Berchuck, Andrew, Murphy, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012928/
https://ncbi.nlm.nih.gov/pubmed/21156726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.108803.110
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