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Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish

BACKGROUND: Increasing use of zebrafish in drug discovery and mechanistic toxicology demands knowledge of cytochrome P450 (CYP) gene regulation and function. CYP enzymes catalyze oxidative transformation leading to activation or inactivation of many endogenous and exogenous chemicals, with consequen...

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Hlavní autoři: Goldstone, Jared V, McArthur, Andrew G, Kubota, Akira, Zanette, Juliano, Parente, Thiago, Jönsson, Maria E, Nelson, David R, Stegeman, John J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012610/
https://ncbi.nlm.nih.gov/pubmed/21087487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-643
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