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Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish

BACKGROUND: Increasing use of zebrafish in drug discovery and mechanistic toxicology demands knowledge of cytochrome P450 (CYP) gene regulation and function. CYP enzymes catalyze oxidative transformation leading to activation or inactivation of many endogenous and exogenous chemicals, with consequen...

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Main Authors: Goldstone, Jared V, McArthur, Andrew G, Kubota, Akira, Zanette, Juliano, Parente, Thiago, Jönsson, Maria E, Nelson, David R, Stegeman, John J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012610/
https://ncbi.nlm.nih.gov/pubmed/21087487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-643
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