Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast

BACKGROUND: Zebrafish express five cytochrome P450 1 genes: CYP1A, CYP1B1, CYP1C1, CYP1C2, inducible by aryl hydrocarbon receptor agonists, and CYP1D1, a constitutively expressed CYP1A-like gene. We examined substrate selectivity of CYP1s expressed in yeast. METHODS: CYP1s were expressed in W(R) yea...

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Pubblicato in:Biochim Biophys Acta
Autori principali: Stegeman, John J., Behrendt, Lars, Woodin, Bruce R., Kubota, Akira, Lemaire, Benjamin, Pompon, Denis, Goldstone, Jared V., Urban, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587093/
https://ncbi.nlm.nih.gov/pubmed/26231923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2015.07.010
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