Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in vivo

Extrahepatic manifestations of hepatitis C virus (HCV) infection occur in 40%-70% of HCV-infected patients. B-cell non-Hodgkin lymphoma is a typical extrahepatic manifestation frequently associated with HCV infection. The mechanism by which HCV infection of B cells leads to lymphoma remains unclear....

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Autors principals: Kasama, Yuri, Sekiguchi, Satoshi, Saito, Makoto, Tanaka, Kousuke, Satoh, Masaaki, Kuwahara, Kazuhiko, Sakaguchi, Nobuo, Takeya, Motohiro, Hiasa, Yoichi, Kohara, Michinori, Tsukiyama-Kohara, Kyoko
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012587/
https://ncbi.nlm.nih.gov/pubmed/20733156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-283358
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