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Follicular dendritic cell–dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion–mediated Bim down-regulation through induction of microRNA-181a

Follicular dendritic cells (FDCs), an essential component of the lymph node microenvironment, regulate and support B-lymphocyte differentiation, survival, and lymphoma progression. Here, we demonstrate that adhesion of mantle cell lymphoma and other non-Hodgkin lymphoma cells to FDCs reduces cell ap...

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Detalhes bibliográficos
Main Authors: Lwin, Tint, Lin, Jianhong, Choi, Yong Sung, Zhang, Xinwei, Moscinski, Lynn C., Wright, Kenneth L., Sotomayor, Eduardo M., Dalton, William S., Tao, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012540/
https://ncbi.nlm.nih.gov/pubmed/20841506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-275925
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