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Follicle-stimulating hormone increases bone mass in female mice

Elevated follicle-stimulating hormone (FSH) activity is proposed to directly cause bone loss independent of estradiol deficiency in aging women. Using transgenic female mice expressing human FSH (TgFSH), we now reveal that TgFSH dose-dependently increased bone mass, markedly elevating tibial and ver...

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Hlavní autoři: Allan, Charles M., Kalak, Robert, Dunstan, Colin R., McTavish, Kirsten J., Zhou, Hong, Handelsman, David J., Seibel, Markus J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012495/
https://ncbi.nlm.nih.gov/pubmed/21149714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012141108
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