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Follicle-stimulating hormone increases bone mass in female mice

Elevated follicle-stimulating hormone (FSH) activity is proposed to directly cause bone loss independent of estradiol deficiency in aging women. Using transgenic female mice expressing human FSH (TgFSH), we now reveal that TgFSH dose-dependently increased bone mass, markedly elevating tibial and ver...

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Detalhes bibliográficos
Main Authors: Allan, Charles M., Kalak, Robert, Dunstan, Colin R., McTavish, Kirsten J., Zhou, Hong, Handelsman, David J., Seibel, Markus J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012495/
https://ncbi.nlm.nih.gov/pubmed/21149714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012141108
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