T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism

We investigated the mechanisms by which T-cell cytokines are able to influence the Toll-like receptor (TLR)-induced, vitamin D-dependent antimicrobial pathway in human monocytes. T-cell cytokines differentially influenced TLR2/1-induced expression of the antimicrobial peptides cathelicidin and DEFB4...

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Hlavní autoři: Edfeldt, Kristina, Liu, Philip T., Chun, Rene, Fabri, Mario, Schenk, Mirjam, Wheelwright, Matthew, Keegan, Caroline, Krutzik, Stephan R., Adams, John S., Hewison, Martin, Modlin, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012480/
https://ncbi.nlm.nih.gov/pubmed/21149724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011624108
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