Vitamin D-directed rheostatic regulation of monocyte antibacterial responses

The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)(2)D) enhances innate immunity by inducing the cathelicidin antimicrobial peptide (hCAP). In monocytes/macrophages, this occurs primarily in response to activation of toll-like receptors (TLR), that induce expression of the vitamin D rec...

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Hlavní autoři: Adams, John S., Ren, Songyang, Liu, Philip T., Chun, Rene F., Lagishetty, Venu, Gombart, Adrian F., Borregaard, Niels, Modlin, Robert L., Hewison, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683618/
https://ncbi.nlm.nih.gov/pubmed/19299728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803736
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