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Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats

BACKGROUND AND PURPOSE: The RhoA/Rho associated kinases (ROCK) pathway has been implicated in the pathophysiology of diabetic nephropathy (DN). Early stages of diabetes are associated with renal haemodynamic changes, contributing to later development of DN. However, the role of RhoA/ROCK, known regu...

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書誌詳細
主要な著者: Komers, R, Oyama, TT, Beard, DR, Anderson, S
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012414/
https://ncbi.nlm.nih.gov/pubmed/20840471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01031.x
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