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Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats

BACKGROUND AND PURPOSE: The RhoA/Rho associated kinases (ROCK) pathway has been implicated in the pathophysiology of diabetic nephropathy (DN). Early stages of diabetes are associated with renal haemodynamic changes, contributing to later development of DN. However, the role of RhoA/ROCK, known regu...

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Autors principals: Komers, R, Oyama, TT, Beard, DR, Anderson, S
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012414/
https://ncbi.nlm.nih.gov/pubmed/20840471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01031.x
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